Mitragyna speciosa (kratom) contains the active alkaloid Mitragynine which is understood to be the alkaloid responsible for its mood enhancement. This alkaloid is notably absent from Mitragyna javanica, but the plant makes up for its absence with mitrajavine that contains the alkaloid ajmalicine that is also in kratom. Ajmalicine is believed to reduce high blood pressure and alleviate stress.
Few people have studied the precise chemistry of Mitragyna javanica so there is little known about its contents. What we can tell you is that it appears to be somewhat effective when compared to kratom.
Kratom contains more than 40 alkaloids including the anticonvulsant Ajmalicine which accounts for its relaxing effects and makes it ideal for those suffering from opiate withdrawal. It also contains the antioxidant Epicatechin, the powerful analgesic 7-hydroxymitragynine, the immunostimulants Isomitraphyline, Isopteropodine and Isorhynchophylline, the dopamine-mediating anti-locomotives Corynoxine A and B, the muscle relaxant Paynantheine, the antihypertensive anti-inflammatory calcium channel blocker Rhynchophyline and the opioid agonist Speciociliatine.
It is unclear whether Mitragyna javanica contains as many active alkaloids as kratom, but what is clear is that it has risen to the top of the heap in terms of kratom alternatives.
Mitragyna javanica has garnered a reputation for offering mild euphoria and sedation. While it is generally considered to be weaker than Mitragyna speciosa, the effects are comparable in similar doses. Like kratom, it grows wild in parts of Southeast Asia, making it the closest compound to raw kratom.
It is the perfect option for those who have never tried kratom before. For first-time users, it is best to start out using Mitragyna javanica even if Mitragyna speciosa is legal in your area as it is milder and, thus, has less potential for adverse effects or accidental overdose.
Like kratom, Mitragyna javanica is user for its mild analgesic properties as well as an anxyiolytic, muscle relaxant and anti-diarrheal. Also like the Mitragyna speciosa plant, Mitragyna javanica has minor sedative effects.
People have been using Mitragyna javanica in Thailand for decades upon decades because, unlike its sister plant Mitragyna speciosa, it is 100% legal. When Mitragyna speciosa was banned in Thailand in the 1940’s, many factory workers turned to Mitragyna javanica to relieve their chronic back pain and other maladies.
It has been a popular folk medicine in its native land for quite some time.